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  Indian J Med Microbiol
 

Figure 2: Resolved structures of severe acute respiratory syndrome coronavirus 2 Mpro and RdRp. (a) A crystal structure of Mpro (PDB: 6Y2F [54]). The structure in cyan color is the Mpro; the molecule in yellow color is a α-ketoamide inhibitor binding to the protein. (b) A cryo-EM structure (PDB: 6M71 [55]) of RdRp (cyan) in complex with co-factors non-structural protein 7 (yellow) and non-structural protein 8 (brown). Blue and red colors on the sphere presentation of the protein structures indicate the positive and negative charged force fields, respectively

Figure 2: Resolved structures of severe acute respiratory syndrome coronavirus 2 M<sup>pro</sup> and RdRp. (a) A crystal structure of M<sup>pro</sup> (PDB: 6Y2F <sup>[54]</sup>). The structure in cyan color is the M<sup>pro</sup>; the molecule in yellow color is a α-ketoamide inhibitor binding to the protein. (b) A cryo-EM structure (PDB: 6M71 <sup>[55]</sup>) of RdRp (cyan) in complex with co-factors non-structural protein 7 (yellow) and non-structural protein 8 (brown). Blue and red colors on the sphere presentation of the protein structures indicate the positive and negative charged force fields, respectively